Molecular Hydrogen Prevents Social Deficits and Depression-Like Behaviors Induced by Low-Intensity Blast in Mice

Author:

Satoh Yasushi1,Araki Yoshiyuki2,Kashitani Masashi3,Nishii Kiyomasa4,Kobayashi Yasushi2,Fujita Masanori5,Suzuki Shinya6,Morimoto Yuji7,Tokuno Shinichi2,Tsumatori Gentaro2,Yamamoto Tetsuo8,Saitoh Daizoh9,Ishizuka Toshiaki1

Affiliation:

1. Department of department of Pharmacology

2. Department of Defense Medicine, National Defense Medical College, Tokorozawa, Japan

3. Department of Aerospace Engineering, National Defense Academy of Japan, Yokosuka, Japan

4. Department of Anatomy and Neurobiology

5. Division of Environmental Medicine, Research Institute

6. Kameda Medical Center, Emergency and Trauma Center, Kamogawa, Chiba, Japan

7. Department of Integrated Physiology Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan

8. Military Medicine Research Unit, Test and Evaluation Command, Japan Ground Self-Defense Force, Setagaya, Tokyo, Japan

9. Division of Traumatology, Research Institute, National Defense Medical College, Tokorozawa, Japan

Funder

Ministry of Defense

Japan Society for the Promotion of Science

Publisher

Oxford University Press (OUP)

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Neurology,General Medicine,Pathology and Forensic Medicine

Reference36 articles.

1. Explosive blast neurotrauma;Ling;J Neurotrauma,2009

2. Mild traumatic brain injury in U.S. Soldiers returning from Iraq;Hoge;N Engl J Med,2008

3. Blood brain barrier dysfunction and delayed neurological deficits in mild traumatic brain injury induced by blast shock waves;Shetty;Front Cell Neurosci,2014

4. Blast induces oxidative stress, inflammation, neuronal loss and subsequent short-term memory impairment in rats;Cho;Neuroscience,2013

5. Blast-associated shock waves result in increased brain vascular leakage and elevated ROS levels in a rat model of traumatic brain injury;Kabu;PLoS One,2015

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