Validation of an Antimicrobial Stewardship-Driven Verigene Blood-Culture Gram-Negative Treatment Algorithm to Improve Appropriateness of Antibiotics-Reference-Cited by-同舟云学术

Validation of an Antimicrobial Stewardship-Driven Verigene Blood-Culture Gram-Negative Treatment Algorithm to Improve Appropriateness of Antibiotics

Published:2018-09-15 Issue:10 Volume:5 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Claeys Kimberly C¹^ORCID,Schlaffer K E²,Heil E L¹,Leekha S³,Johnson J K⁴

Affiliation:

1. University of Maryland School of Pharmacy, Department of Pharmacy Practice and Science, Baltimore

2. University of Maryland Medical System, Department of Medicine, Baltimore

3. University of Maryland School of Medicine, Departments of Epidemiology and Public Health, Baltimore

4. University of Maryland School of Medicine, Department of Pathology, Baltimore

Abstract

Abstract Rapid diagnostic testing (RDT) allows for early adjustment of antibiotic therapy. This study examined the potential impact of a stewardship-driven antibiotic treatment algorithm, incorporating RDT into the management of Gram-negative bacteremia. The proposed algorithm would have resulted in 88.4% of cases receiving appropriate antibiotic therapy versus 78.1% by standard of care (P = .014).

Funder

Applied Biocode

ALK Abello

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/5/10/ofy233/33576247/ofy233.pdf

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