The antimicrobial resistome in relation to antimicrobial use and biosecurity in pig farming, a metagenome-wide association study in nine European countries

Author:

Van Gompel Liese1ORCID,Luiken Roosmarijn E C1,Sarrazin Steven2,Munk Patrick3ORCID,Knudsen Berith E3,Hansen Rasmus B4,Bossers Alex15ORCID,Aarestrup Frank M3ORCID,Dewulf Jeroen2ORCID,Wagenaar Jaap A56,Mevius Dik J56,Schmitt Heike17,Heederik Dick J J1,Dorado-García Alejandro1,Smit Lidwien A M1,Graveland Haitske,van Essen Alieda,Gonzalez-Zorn Bruno,Moyano Gabriel,Sanders Pascal,Chauvin Claire,David Julie,Battisti Antonio,Caprioli Andrea,Blaha Thomas,Wadepohl Katharina,Brandt Maximiliane,Hald Tine,Duarte Ana Sofia Ribeiro,Wasyl Dariusz,Skarżyńska Magdalena,Zając Magdalena,Hoszowski Andrzej,Daskalov Hristo,Saatkamp Helmut W,Stärk Katharina D C,

Affiliation:

1. Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 2, CM Utrecht, The Netherlands

2. Veterinary Epidemiology Unit, Department of Reproduction, Obstetrics and Herd Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, Belgium

3. Research Group for Genomic Epidemiology, National Food Institute, Technical University of Denmark, Kemitorvet 204, Kongens Lyngby, Denmark

4. Intomics A/S, Lottenborgvej 26, Kongens Lyngby, Denmark

5. Wageningen Bioveterinary Research, Houtribweg 39, RA, Lelystad, The Netherlands

6. Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, CL, Utrecht, The Netherlands

7. Centre of Infectious Disease Control, National Institute for Public Health and the Environment, Antonie van Leeuwenhoeklaan 9, MA, Bilthoven, The Netherlands

Funder

Ecology from Farm to Fork Of microbial drug Resistance and Transmission

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

Reference59 articles.

1. The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2014;EFSA J,2016

2. Antibacterial drug discovery in the resistance era;Brown;Nature,2016

3. ECDC/EFSA/EMA second joint report on the integrated analysis of the consumption of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from humans and food‐producing animals;EFSA J,2017

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