1. Clinic III for Internal Medicine (Department of Cardiology), Heart Center at the University Hospital Cologne , Kerpener Str. 62, D-50937 Cologne , Germany
2. Cologne Cardiovascular Research Center (CCRC), Hospital Cologne and Medical Faculty, Heart Center at the University, University of Cologne , Cologne , Germany
3. Department of Respiratory Medicine and Infectious Diseases, Hannover Medical School , Hannover , Germany
4. German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH) , Hannover , Germany
5. Department of Medicine, University of Maryland School of Medicine , Baltimore, MD , USA
6. The University of Maryland-Institute for Health Computing , Bethesda, MD , USA