Polygenic scores in real-world cardiovascular risk prediction: the path forward for assessing worth?
Author:
Affiliation:
1. Massachusetts General Hospital and Harvard Medical School , Simches Research Building, 3.128, 185 Cambridge St, Boston, MA 02114 , USA
2. Broad Institute of MIT and Harvard , Cambridge, MA , USA
Publisher
Oxford University Press (OUP)
Link
https://academic.oup.com/eurheartj/article-pdf/45/34/3161/59035404/ehae442.pdf
Reference15 articles.
1. European Society of Cardiology: cardiovascular disease statistics 2021;Timmis;Eur Heart J,2022
2. Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants;Aragam;Nat Genet,2022
3. A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease;Patel;Nat Med,2023
4. Do polygenic risk scores improve patient selection for prevention of coronary artery disease?;Khan;JAMA,2020
5. Genomic prediction of coronary heart disease;Abraham;Eur Heart J,2016
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