Big data from electronic health records for early and late translational cardiovascular research: challenges and potential

Author:

Hemingway Harry12,Asselbergs Folkert W123,Danesh John4,Dobson Richard125,Maniadakis Nikolaos6,Maggioni Aldo6,van Thiel Ghislaine J M3,Cronin Maureen7,Brobert Gunnar8,Vardas Panos6,Anker Stefan D910,Grobbee Diederick E11,Denaxas Spiros12,

Affiliation:

1. Research Department of Clinical Epidemiology, The Farr Institute of Health Informatics Research, University College London, 222 Euston Road, London NW1 2DA, UK

2. The National Institute for Health Research, Biomedical Research Centre, University College London Hospitals NHS Foundation Trust, University College London, 222 Euston Road, London NW1 2DA, UK

3. Department of Cardiology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands

4. MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Worts Causeway, Cambridge CB1 8RN, UK

5. NIHR Biomedical Research Centre for Mental Health (IOP), King‘s College London, De Crespigny Park, London SE5 8AF, UK

6. European Society of Cardiology (ESC), 2035 Route des Colles, Les Templiers - CS 80179 Biot, 06903 Sophia Antipolis, France

7. Vifor Pharma Ltd, lughofstrasse 61, 8152 Glattbrugg, Zurich, Switzerland

8. Department of Epidemiology, Bayer Pharma AG, Müllerstrasse 178, 13353 Berlin, Germany

9. Division of Cardiology and Metabolism—Heart Failure, Cachexia & Sarcopenia; Department of Cardiology (CVK), Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité University Medicine, Charitépl. 1, 10117 Berlin, Germany

10. Department of Cardiology and Pneumology, University Medicine Göttingen (UMG), Robert-Koch-Strasse 40, 37099, Göttingen, Germany

11. Julius Centre for Health Sciences and Primary Care, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands

Funder

Medical Research Council

Arthritis Research UK

British Heart Foundation

Cancer Research UK

Chief Scientist Office

Economic and Social Research Council

Engineering and Physical Sciences Research Council

Wellcome Trust

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

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