PhysiBoSS: a multi-scale agent-based modelling framework integrating physical dimension and cell signalling

Author:

Letort Gaelle123ORCID,Montagud Arnau123ORCID,Stoll Gautier4567,Heiland Randy8,Barillot Emmanuel123,Macklin Paul8,Zinovyev Andrei123,Calzone Laurence123

Affiliation:

1. Institut Curie, PSL Research University, Paris, France

2. INSERM, U900, Paris, France

3. CBIO-Centre for Computational Biology, MINES ParisTech, PSL Research University, Paris, France

4. Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France

5. Gustave Roussy Cancer Campus, Villejuif, France

6. INSERM, U1138, Paris, France

7. Equipe 11 Labellisée par la Ligue Nationale Contre le Cancer, Centre de Recherche des Cordeliers, Paris, France

8. Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA

Funder

European Union Horizon 2020 research and innovation program

Chemotaxis project

INVADE

ITMO Cancer

Breast Cancer Research Foundation

Jayne Koskinas Ted Giovanis Foundation for Health and Policy

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

Reference76 articles.

1. Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion;Ahmadzadeh;Proc. Natl. Acad. Sci,2017

2. An automaton model for the cell cycle;Altinok;Interface Focus,2011

3. Agent-based models in translational systems biology;An;Wiley Interdisciplinary Reviews: Systems Biology and Medicine,2009

4. Integrative mathematical oncology;Anderson;Nat. Rev. Cancer,2008

5. Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment;Anderson;Cell,2006

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