Chronic and Neurotropic: A Paradigm-Challenging Case of Dengue Virus Encephalitis in a Patient With Advanced HIV Infection-Reference-Cited by-同舟云学术

Chronic and Neurotropic: A Paradigm-Challenging Case of Dengue Virus Encephalitis in a Patient With Advanced HIV Infection

Published:2024-02-06 Issue:2 Volume:79 Page:498-501
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Marinelli Tina¹^ORCID,Masters Jeffrey¹²,Buckland Michael E³⁴,Lee Maggie³,Rawlinson William⁵⁶,Kim Ki Wook⁶,Urriola Nicolas⁷,van Hal Sebastiaan¹

Affiliation:

1. Department of Infectious Diseases and Microbiology, Royal Prince Alfred Hospital , Sydney, New South Wales , Australia

2. Kirby Institute, University of New South Wales , Sydney, New South Wales , Australia

3. Department of Neuropathology, Royal Prince Alfred Hospital , Sydney, New South Wales , Australia

4. School of Medical Sciences, University of Sydney , Sydney, New South Wales , Australia

5. Serology and Virology Division, Department of Microbiology, New South Wales Health Pathology , Sydney, New South Wales , Australia

6. School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales , Sydney, New South Wales , Australia

7. Department of Clinical Immunology and Allergy, Royal Prince Alfred Hospital , Sydney, New South Wales , Australia

Abstract

Abstract A 32-year-old female with advanced human immunodeficiency virus infection presented to an Australian hospital with subacute, worsening symptoms of encephalitis. Metagenomic sequencing and Dengue NS3 antigen staining of brain tissue confirmed active dengue virus (DENV) encephalitis. The most recent possible DENV exposure was months prior in West Africa, indicating chronicity.

Funder

Juvenile Diabetes Research Foundation

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciae061/56746593/ciae061.pdf

Reference17 articles.

1. IDseq;Kalantar;Gigascience,2020

2. Neurologic manifestations of dengue infection;Solomon;Lancet,2000

3. Neurological manifestations in dengue patients;Pancharoen;Southeast Asian J Trop Med Public Health,2001

4. Dengue infection with central nervous system manifestations;Thisyakorn;Southeast Asian J Trop Med Public Health,1999