The bovine protein α-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress

Author:

Markus C Rob1,Olivier Berend1,Panhuysen Geert EM1,Van der Gugten Jan1,Alles Martine S1,Tuiten Adriaan1,Westenberg Herman GM1,Fekkes Durk1,Koppeschaar Hans F1,de Haan Edward EHF1

Affiliation:

1. From the TNO Nutrition and Food Research Institute, Zeist, Netherlands; the Department of Psychopharmacology, University Utrecht, Utrecht, Netherlands; Friesland Coberco Dairy Foods, Research Center, Deventer, Netherlands; the Departments of Biological Psychiatry and Endocrinology, University Hospital Utrecht, Utrecht, Netherlands; and the Department of Psychiatry, Erasmus University, Rotterdam,

Publisher

Oxford University Press (OUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference53 articles.

1. Stress-induced release of 5-HT in the hippocampus and its dependence on increased tryptophan availability: an in vivo electrochemical study;Joseph;Brain Res,1983

2. Monoamines in response and adaptation to stress;Stanford,1993

3. The serotonin hypothesis of major depression;Maes,1995

4. Depression;Van Praag;Lancet,1982

5. Multiple neurochemical and behavioral consequences of stressors: implications for depression;Anisman,1991

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