Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity-Reference-Cited by-同舟云学术

Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity

Published:2018-04-19 Issue:9 Volume:46 Page:4819-4830
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Dolot Rafal¹,Lam Curtis H²,Sierant Malgorzata¹,Zhao Qiang³,Liu Feng-Wu⁴,Nawrot Barbara¹,Egli Martin⁵,Yang Xianbin²

Affiliation:

1. Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, 90–363 Lodz, Sienkiewicza 112, Poland

2. AM Biotechnologies, LLC, 12521 Gulf Freeway, Houston, TX 77034, USA

3. State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China

4. School of Pharmaceutical Sciences, Zhengzhou University, Science Avenue 100, Zhengzhou 450001, Henan, China

5. Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, TN 37232, USA

Funder

National Institutes of Health

National Natural Science Foundation of China

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/46/9/4819/24829775/gky268.pdf

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