Organoids in COVID-19: can we break the glass ceiling?-Reference-Cited by-同舟云学术

Organoids in COVID-19: can we break the glass ceiling?

Published:2023-08-25 Issue:1 Volume:115 Page:85-99
ISSN:1938-3673
Container-title:Journal of Leukocyte Biology
language:en
Short-container-title:

Author:

Chau Chiu Wang¹,Sugimura Ryohichi¹²^ORCID

Affiliation:

1. School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, University of Hong Kong , 21 Sassoon Rd, Pokfulam 99077 , Hong Kong

2. Centre for Translational Stem Cell Biology , 17 Science Park W Ave, Science Park 999077 , Hong Kong

Abstract

Abstract COVID-19 emerged in September 2020 as a disease caused by the virus SARS-CoV-2. The disease presented as pneumonia at first but later was shown to cause multisystem infections and long-term complications. Many efforts have been put into discovering the exact pathogenesis of the disease. In this review, we aim to discuss an emerging tool in disease modeling, organoids, in the investigation of COVID-19. This review will introduce some methods and breakthroughs achieved by organoids and the limitations of this system.

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Immunology,Immunology and Allergy

Link

https://academic.oup.com/jleukbio/advance-article-pdf/doi/10.1093/jleuko/qiad098/52138411/qiad098.pdf

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