Mediastinal transposition of the greater omentum for treatment of infected prostheses of the ascending aorta and aortic arch

Author:

Pitts Leonard12ORCID,Pasic Miralem123ORCID,Wert Leonhard12ORCID,Nersesian Gaik12ORCID,Kaemmel Julius12,Buz Semih123,Knosalla Christoph123,Düsterhöft Volker12,Starck Christoph123,Kempfert Jörg123ORCID,Jacobs Stephan123,Falk Volkmar1234ORCID

Affiliation:

1. Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité (DHZC) , Berlin, Germany

2. Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin , Berlin, Germany

3. DZHK (German Centre for Cardiovascular Research), partner site Berlin , Berlin, Germany

4. Translational Cardiovascular Technologies, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) , Zurich, Switzerland

Abstract

Abstract OBJECTIVES The aim of this study was to evaluate the outcomes of transposition of the omentum into the mediastinum to support the replacement of infected aortic grafts or to cover infected aortic grafts that are not amenable for surgical replacement. METHODS All patients with thoracic aortic graft infections who underwent mediastinal transposition of the omentum at our institution between 2005 and 2023 were included in this study. Mediastinal transposition of the omentum was performed either after replacement of the infected graft (‘curative concept’) or solely as bailout procedure by wrapping the infected graft (‘palliative concept’). The diagnosis, including computed tomography scans during follow-up, was made according to the criteria of the Management of Aortic Graft Infection Collaboration. RESULTS The patient cohort consisted of 31 patients. Both in-hospital and 1-year mortality were 0% (n = 0) for the curative concept (n = 9) compared to 23% (n = 5) and 41% (n = 9) for the palliative concept (n = 22), respectively. There was no graft infection-associated death or recurrence of infection after 3 years in the curative group. Survival was 52% at 3 years in the palliative group, with freedom of infection in 59% of the patients (n = 13). CONCLUSIONS Transposition of the omentum and wrapping of the infected aortic prosthetic graft is a useful bailout strategy for patients who are ineligible for replacement of an infected aortic graft. However, mortality stays high. For radical treatment of aortic graft infections, it may prove an effective supportive therapy and represents an important tool in the armamentarium of cardiac surgeons.

Publisher

Oxford University Press (OUP)

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1. Die AMDS-Hybridprothese – ein neues Device zur Behandlung der akuten Typ-A-Dissektion;Zeitschrift für Herz-,Thorax- und Gefäßchirurgie;2024-09-13

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