External dose estimates of laboratory rats and mice during exposure to dispersed neutron-activated 56Mn powder-Reference-Cited by-同舟云学术

External dose estimates of laboratory rats and mice during exposure to dispersed neutron-activated 56Mn powder

Published:2022-08-13 Issue:Supplement_1 Volume:63 Page:i16-i20
ISSN:0449-3060
Container-title:Journal of Radiation Research
language:en
Short-container-title:

Author:

Stepanenko Valeriy¹,Sato Hitoshi²,Fujimoto Nariaki³,Shichijo Kazuko⁴,Toyoda Shin⁵,Kawano Noriyuki⁶,Endo Satoru⁷,Kaprin Andrey⁸,Ivanov Sergey¹,Shegay Peter⁸,Petukhov Alexey¹,Kolyzhenkov Timofey¹,Bogacheva Victoria¹,Chaizhunusova Nailya⁹,Shabdarbaeva Dariya⁹,Zhumadilov Kassym¹⁰,Hoshi Masaharu³

Affiliation:

1. A. Tsyb Medical Radiological Research Center – Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation , Koroleva Str., 4., Obninsk, Kaluga Region 2490036, Russian Federation

2. Ibaraki Prefectural University of Health Sciences , 4669-2, Ami-machi, Inashiki-gun, Ibaraki 300-0394, Japan

3. Research Institute for Radiation Biology and Medicine, Hiroshima University , 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8551, Japan

4. Atomic Bomb Disease Institute, Nagasaki University , 1-12-4, Sakamoto, Nagasaki 852-8102, Japan

5. Department of Applied Physics, Okayama University of Science , 1-1 Ridai, Kita-ku, Okayama 700-0005, Japan

6. The Center for Peace, Hiroshima University , Higashisenda-machi 1-1-89, Naka-ku, Hiroshima 730-0053, Japan

7. Graduate School of Advanced Science and Engineering, Hiroshima University , 1-4-1 Kagamiyama, Higashi- Hiroshima 739-8527, Japan

8. National Medical Research Radiological Center of the Ministry of Health of the Russian Federation , Koroleva Str., 4., Obninsk, Kaluga Region 2490036, Russian Federation

9. Semey State Medical University , Abay Str., 103, Semey, 071400, Kazakhstan

10. L.N. Gumilyov Eurasian National University , Munaipasova Str. 13, Nur Sultan 010008, Kazakhstan

Abstract

Abstract Estimates of external absorbed dose in experimental animals exposed to sprayed neutron-activated 56Mn powder are necessary for comparison with internal absorbed doses estimated under the same exposure conditions, which is required for a correct interpretation of the observed biological effects. It has been established that the measured dose of external absorbed dose as a result of gamma irradiation range 1–15 mGy, which is order of magnitude less than the maximal dose of internal gamma and beta irradiation of the whole body of the same experimental animals irradiated under the same conditions: according to the available literature data, the maximal values of absorbed dose of internal gamma-beta irradiation of the whole body are in the range of 330 mGy–1200 mGy for mice and 100 mGy–150 mGy for rats. It is concluded that under the conditions of experiments with dispersed neutron-activated powder 56MnO2, internal gamma-beta irradiation of experimental animals is the main factor of radiation exposure compared to external gamma irradiation.

Funder

Grants-in-Aid for Scientific Research

JSPS KAKENHI

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Radiology, Nuclear Medicine and imaging,Radiation

Link

https://academic.oup.com/jrr/article-pdf/63/Supplement_1/i16/48517134/rrac032.pdf

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