Identification of Chemical Compounds that Induce HIF-1α Activity-Reference-Cited by-同舟云学术

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Identification of Chemical Compounds that Induce HIF-1α Activity

Published:2009-06-05 Issue:1 Volume:112 Page:153-163
ISSN:1096-6080
Container-title:Toxicological Sciences
language:en
Short-container-title:

Author:

Xia Menghang,Huang Ruili,Sun Yi,Semenza Gregg L.,Aldred Shelley Force,Witt Kristine L.,Inglese James,Tice Raymond R.,Austin Christopher P.

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Link

http://academic.oup.com/toxsci/article-pdf/112/1/153/16680641/kfp123.pdf

Reference43 articles.

1. Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors;Cancer Res.,2005

2. Hypoxia induces pivotal tumor angiogenesis control factors including p53, vascular endothelial growth factor and the NFkappaB-dependent inducible nitric oxide synthase and cyclooxygenase-2;J. Cancer Res. Clin. Oncol.,1999

3. Clioquinol, a Cu(II)/Zn(II) chelator, inhibits both ubiquitination and asparagine hydroxylation of hypoxia-inducible factor-1alpha, leading to expression of vascular endothelial growth factor and erythropoietin in normoxic cells;J. Biol. Chem.,2006

4. Toxicology. Transforming environmental health protection;Science,2008

5. Melatonin modulates the expression of VEGF and HIF-1α induced by CoCl2 in cultured cancer cells;J. Pineal Res.,2008

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