A 3D Human Airway Model Enables Prediction of Respiratory Toxicity of Inhaled Drugs In Vitro-Reference-Cited by-同舟云学术

A 3D Human Airway Model Enables Prediction of Respiratory Toxicity of Inhaled Drugs In Vitro

Published:2017-11-22 Issue:1 Volume:162 Page:301-308
ISSN:1096-6080
Container-title:Toxicological Sciences
language:en
Short-container-title:

Author:

Balogh Sivars Kinga¹,Sivars Ulf²,Hornberg Ellinor²,Zhang Hui³,Brändén Lena²,Bonfante Rosy⁴,Huang Song⁴,Constant Samuel⁴,Robinson Ian⁵,Betts Catherine J³,Åberg Per M⁵

Affiliation:

1. Discovery Safety, Drug Safety and Metabolism

2. Respiratory, Inflammation and Autoimmunity

3. Pathology, Drug Safety and Metabolism

4. Epithelix Sàrl, CH-1228 Geneva, Switzerland

5. Regulatory Safety, Drug Safety and Metabolism

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Link

http://academic.oup.com/toxsci/article-pdf/162/1/301/24141523/kfx255.pdf

Reference30 articles.

1. Predicting toxicities in humans by nonclinical safety testing: An update with particular reference to anticancer compounds;Ahuja;Drug Discov. Today,2017

2. Clinical expert panel on monitoring potential lung toxicity of inhaled oligonucleotides: Consensus points and recommendations;Alton;Nucleic. Acid Ther,2012

3. An in vitro approach to assess the toxicity of inhaled tobacco smoke components: Nicotine, cadmium, formaldehyde and urethane;Balharry;Toxicology,2008

4. Evaluating the toxicity of cigarette whole smoke solutions in an air-liquid-interface human in vitro airway tissue model;Cao;Toxicol. Sci,2017

5. Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma;Chauhan;Cochrane Database Syst. Rev,2014

Cited by 69 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Complex in vitro models positioned for impact to drug testing in pharma: a review;Biofabrication;2024-08-27

2. Chemical respiratory sensitization—Current status of mechanistic understanding, knowledge gaps and possible identification methods of sensitizers;Frontiers in Toxicology;2024-07-29

3. A novel in vitro high-content imaging assay for the prediction of drug-induced lung toxicity;Archives of Toxicology;2024-05-28

4. A Novel Bionebulizer Approach to Study the Effects of Natural Mineral Water on a 3D In Vitro Nasal Model from Allergic Rhinitis Patients;Biomedicines;2024-02-09

5. Nitric oxide-releasing prodrug for the treatment of complex Mycobacterium abscessus infections;Antimicrobial Agents and Chemotherapy;2024-02-07