Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation-Reference-Cited by-同舟云学术

Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation

Published:2009-12-08 Issue:5 Volume:19 Page:790-802
ISSN:1460-2083
Container-title:Human Molecular Genetics
language:en
Short-container-title:

Author:

Gremer Lothar,De Luca Alessandro,Merbitz-Zahradnik Torsten,Dallapiccola Bruno,Morlot Susanne,Tartaglia Marco,Kutsche Kerstin,Ahmadian Mohammad Reza,Rosenberger Georg

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

Link

http://academic.oup.com/hmg/article-pdf/19/5/790/17250719/ddp548.pdf

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