Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymerase
Author:
Affiliation:
1. Centro de Biología Molecular ‘Severo Ochoa’ (CSIC-UAM), Cantoblanco, E-28049 Madrid, Spain
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/45/15/9046/25367302/gkx633.pdf
Reference59 articles.
1. PrimPol, an archaic primase/polymerase operating in human cells;Garcia-Gomez;Mol. Cell,2013
2. DNA primases;Frick;Annu. Rev. Biochem.,2001
3. Repriming of DNA synthesis at stalled replication forks by human PrimPol;Mouron;Nat. Struct. Mol. Biol.,2013
4. Molecular dissection of the domain architecture and catalytic activities of human PrimPol;Keen;Nucleic Acids Res.,2014
5. hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity;Wan;EMBO Rep.,2013
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