Cognitive correlates of α4β2 nicotinic acetylcholine receptors in mild Alzheimer’s dementia

Author:

Sabri Osama1,Meyer Philipp M1,Gräf Susanne23,Hesse Swen14,Wilke Stephan1,Becker Georg-Alexander1,Rullmann Michael134,Patt Marianne1,Luthardt Julia1,Wagenknecht Gudrun5,Hoepping Alexander6,Smits Rene6,Franke Annegret7,Sattler Bernhard1,Tiepolt Solveig1,Fischer Steffen8,Deuther-Conrad Winnie8,Hegerl Ulrich2,Barthel Henryk1,Schönknecht Peter2,Brust Peter8

Affiliation:

1. Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany

2. Department of Psychiatry and Psychotherapy, University of Leipzig, Leipzig, Germany

3. Max-Planck-Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

4. Integrated Research and Treatment Centre (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany

5. Central Institute for Engineering, Electronics and Analytics—Electronic Systems (ZEA-2), Forschungszentrum Jülich, Jülich, Germany

6. ABX Advanced Biochemical Compounds GmbH, Radeberg, Germany

7. Centre for Clinical Trials Leipzig, University of Leipzig, Leipzig, Germany

8. Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Research Site Leipzig, Leipzig, Germany

Funder

BMBF

Publisher

Oxford University Press (OUP)

Subject

Neurology (clinical)

Reference71 articles.

1. Frequent amyloid deposition without significant cognitive impairment among the elderly;Aizenstein;Arch Neurol,2008

2. A fast diffeomorphic image registration algorithm;Ashburner;Neuroimage,2007

3. Basal forebrain cholinergic circuits and signaling in cognition and cognitive decline;Ballinger;Neuron,2016

4. The role of positron emission tomography imaging in understanding Alzheimer's disease;Barthel;Expert Rev Neurother,2015

5. Controlling the false discovery rate: a practical and powerful approach to multiple testing;Benjamini;J R Stat Soc Series B Methodol,1995

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