Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model

Author:

Tagge Chad A12,Fisher Andrew M12,Minaeva Olga V123,Gaudreau-Balderrama Amanda12,Moncaster Juliet A134,Zhang Xiao-Lei5,Wojnarowicz Mark W14,Casey Noel16,Lu Haiyan7,Kokiko-Cochran Olga N7,Saman Sudad8,Ericsson Maria9,Onos Kristen D10,Veksler Ronel11,Senatorov Vladimir V12,Kondo Asami13,Zhou Xiao Z13,Miry Omid5,Vose Linnea R5,Gopaul Katisha R5,Upreti Chirag5,Nowinski Christopher J414,Cantu Robert C41415,Alvarez Victor E1416,Hildebrandt Audrey M16,Franz Erich S12,Konrad Janusz2,Hamilton James A4,Hua Ning4,Tripodis Yorghos1417,Anderson Andrew T18,Howell Gareth R10,Kaufer Daniela1219,Hall Garth F8,Lu Kun P13,Ransohoff Richard M7,Cleveland Robin O20,Kowall Neil W41416,Stein Thor D41416,Lamb Bruce T7,Huber Bertrand R4141621,Moss William C18,Friedman Alon1122,Stanton Patric K5,McKee Ann C41416,Goldstein Lee E12346

Affiliation:

1. Molecular Aging and Development Laboratory, Boston University School of Medicine, Boston, MA 02118, USA

2. Boston University College of Engineering, Boston, MA 02215, USA

3. Boston University Photonics Center, Boston University, Boston, MA 02215, USA

4. Boston University School of Medicine, Boston, MA 02118, USA

5. Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY 10595, USA

6. The Center for Biometals and Metallomics, Boston University School of Medicine, Boston, MA 02118, USA

7. Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA

8. Department of Biological Sciences, University of Massachusetts Lowell, Lowell, MA 01854, USA

9. Electron Microscope Facility, Harvard Medical School, Boston, MA 02115, USA

10. The Jackson Laboratory, Bar Harbor, ME 04609, USA

11. Departments of Brain and Cognitive Sciences, Physiology and Cell Biology, Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel

12. Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA

13. Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA

14. Alzheimer’s Disease Center, CTE Program, Boston University School of Medicine, Boston, MA 02118, USA

15. Department of Neurosurgery, Emerson Hospital, Concord, MA 01742, USA

16. VA Boston Healthcare System, Boston, MA 02130, USA

17. Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA

18. Lawrence Livermore National Laboratory, Livermore, CA 94551, USA

19. Department of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA

20. Institute of Biomedical Engineering, University of Oxford, Oxford OX3 7DQ, UK

21. National Center for PTSD, VA Boston Healthcare System, Boston, MA 02130, USA

22. Department of Medical Neuroscience, Brain Repair Center, Dalhousie University, Halifax, B3H 4R2, Canada

Funder

National Institutes of Health

University of California

U.S. Department of Defense

Israel Science Foundation

National Operating Committee on Standards for Athletic Equipment

Publisher

Oxford University Press (OUP)

Subject

Clinical Neurology

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