Interictal epileptiform discharges shape large-scale intercortical communication-Reference-Cited by-同舟云学术

Interictal epileptiform discharges shape large-scale intercortical communication

Published:2019-09-09 Issue:11 Volume:142 Page:3502-3513
ISSN:0006-8950
Container-title:Brain
language:en
Short-container-title:

Author:

Dahal Prawesh¹,Ghani Naureen²,Flinker Adeen³⁴,Dugan Patricia³⁴,Friedman Daniel³⁴,Doyle Werner⁴⁵,Devinsky Orrin³⁴,Khodagholy Dion¹,Gelinas Jennifer N²⁶

Affiliation:

1. Department of Electrical Engineering, Columbia University, New York, NY, USA

2. Institute for Genomic Medicine, Columbia University Medical Center, New York, NY, USA

3. Department of Neurology, NYU Langone, New York, NY, USA

4. Comprehensive Epilepsy Center, NYU Langone, New York, NY, USA

5. Department of Neurosurgery, NYU Langone, New York, NY, USA

6. Department of Neurology, Columbia University Medical Center, New York, NY, USA

Abstract

Focal epilepsy is associated with large-scale brain dysfunction. Dahal et al. reveal that interictal epileptiform discharges modulate normal brain rhythms in regions beyond the epileptic network, potentially impairing processes that rely heavily upon intercortical communication, such as cognition and memory.

Funder

CURE

FACES

Department of Neurology

Institute for Genomic Medicine at Columbia University Irving Medical Center

Publisher

Oxford University Press (OUP)

Subject

Clinical Neurology

Link

http://academic.oup.com/brain/article-pdf/142/11/3502/30329898/awz269.pdf

Reference60 articles.