Silent cerebral lesions following catheter ablation for atrial fibrillation: a state-of-the-art review

Author:

Calvert Peter12ORCID,Kollias Georgios3ORCID,Pürerfellner Helmut3ORCID,Narasimhan Calambur4ORCID,Osorio Jose5ORCID,Lip Gregory Y H126ORCID,Gupta Dhiraj12ORCID

Affiliation:

1. Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital , Liverpool , UK

2. Department of Cardiology, Liverpool Heart & Chest Hospital NHS Foundation Trust , Thomas Drive, Liverpool L14 3PE , UK

3. Ordensklinikum Linz Elisabethinen , Linz , Austria

4. Department of Cardiac Electrophysiology, AIG Hospitals , 1-66/AIG/2 to 5, Mindspace Road, Gachibowli Hyderabad, Telangana 500032 , India

5. Grandview Medical Center, Arrhythmia Institute at Grandview , 3686 Grandview Parkway Suite 720, Birmingham, AL 35243 , USA

6. Danish Centre for Clinical Health Services Research, Aalborg University , Aalborg , Denmark

Abstract

Abstract Atrial fibrillation is associated with neurocognitive comorbidities such as stroke and dementia. Evidence suggests that rhythm control—especially if implemented early—may reduce the risk of cognitive decline. Catheter ablation is highly efficacious for restoring sinus rhythm in the setting of atrial fibrillation; however, ablation within the left atrium has been shown to result in MRI-detected silent cerebral lesions. In this state-of-the-art review article, we discuss the balance of risk between left atrial ablation and rhythm control. We highlight suggestions to lower the risk, as well as the evidence behind newer forms of ablation such as very high power short duration radiofrequency ablation and pulsed field ablation.

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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