Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site

Author:

Melnikov Sergey V1,Khabibullina Nelli F2,Mairhofer Elisabeth3,Vargas-Rodriguez Oscar1,Reynolds Noah M1,Micura Ronald3,Söll Dieter14,Polikanov Yury S25ORCID

Affiliation:

1. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA

2. Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA

3. Institute of Organic Chemistry at Leopold Franzens University, A-6020 Innsbruck, Austria

4. Department of Chemistry, Yale University, New Haven, CT 06520, USA

5. Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, IL 60607, USA

Funder

National Institutes of Health

Austrian Science Fund

National Institute of General Medical Sciences

Health Effects Institute

Argonne National Laboratory

Publisher

Oxford University Press (OUP)

Subject

Genetics

Reference72 articles.

1. Emerging knowledge of regulatory roles of D-amino acids in bacteria;Cava;Cell. Mol. Life Sci.,2011

2. Bacterial synthesis of D-amino acids;Radkov;Appl. Microbiol. Biotechnol.,2014

3. GC-MS analysis of diaminopimelic acid stereoisomers and amino acid enantiomers in rumen bacteria;Schieber;Biomed. Chromatogr.,1999

4. Separation and sensitive detection of D-amino acids in biological matrices;Kirschner;J. Sep. Sci.,2009

5. D-amino acids in the nervous and endocrine systems;Kiriyama;Scientifica (Cairo),2016

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