MEHMO syndrome mutationEIF2S3-I259Mimpairs initiator Met-tRNAiMet binding to eukaryotic translation initiation factor eIF2
Author:
Affiliation:
1. Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
2. National Institute of General Medical Sciences, National Institutes of Health, Bethesda, MD 20892, USA
Funder
National Institute of General Medical Sciences
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/47/2/855/27581899/gky1213.pdf
Reference48 articles.
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2. The mechanism of eukaryotic translation initiation: new insights and challenges;Hinnebusch;Cold Spring Harb. Perspect. Biol.,2012
3. Molecular mechanism of scanning and start codon selection in eukaryotes;Hinnebusch;Microbiol. Mol. Biol. Rev.,2011
4. Mutations in GCD11, the structural gene for eIF2γ in yeast, alter translational regulation of GCN4 and the selection of the start site for protein synthesis;Dorris;EMBO J.,1995
5. Translation initiation factor 2γ mutant alters start codon selection independent of Met-tRNA binding;Alone;Mol. Cell. Biol.,2008
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