A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing-Reference-Cited by-同舟云学术

A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing

Published:2018-03-14 Issue:8 Volume:46 Page:4054-4071
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Wang Pei-Hui¹,Fung Sin-Yee¹,Gao Wei-Wei¹,Deng Jian-Jun¹,Cheng Yun¹,Chaudhary Vidyanath¹,Yuen Kit-San¹,Ho Ting-Hin¹,Chan Ching-Ping¹,Zhang Yan²,Kok Kin-Hang³,Yang Wanling²,Chan Chi-Ping¹,Jin Dong-Yan¹

Affiliation:

1. School of Biomedical Sciences, The University of Hong Kong, Pokfulam, Hong Kong

2. Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Pokfulam, Hong Kong

3. Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong

Funder

Hong Kong Health and Medical Research Fund

Hong Kong Research Grants Council

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/46/8/4054/24783234/gky186.pdf

Reference73 articles.

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3. The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells;Zhang;Nat. Immunol.,2011

4. IFI16 is an innate immune sensor for intracellular DNA;Unterholzner;Nat. Immunol.,2010

5. DNA-PK is a DNA sensor for IRF-3-dependent innate immunity;Ferguson;Elife,2012

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