Prevalence of Immunoglobulin G (IgG) Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Evaluation of a Rapid MEDsan IgG Test in Children Seeking Medical Care-Reference-Cited by-同舟云学术

Prevalence of Immunoglobulin G (IgG) Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Evaluation of a Rapid MEDsan IgG Test in Children Seeking Medical Care

Published:2020-11-08 Issue:7 Volume:72 Page:e192-e195
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Posfay-Barbe Klara M¹,Andrey Diego O²³,Virzi Julien²,Cohen Patrick²,Pigny Fiona²,Goncalves Ana R²,Pinosch Selina¹,Lacroix Laurence¹,Stringhini Silvia⁴,Kaiser Laurent²³,Vuilleumier Nicolas²,L’Huillier Arnaud G¹²

Affiliation:

1. Department of Woman, Child, and Adolescent Medicine, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland

2. Department of Diagnostics, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland

3. Department of Medicine, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland

4. Department of Primary Care Medicine, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland

Abstract

Abstract In 208 children seeking medical care, the seropositivity rate of anti–SARS-CoV-2 IgG antibodies was 8.7%, suggesting an infection rate similar to that observed in adults but >100-fold the incidence of RT-PCR–confirmed pediatric cases. Compared with the gold-standard combined ELISA + immunofluorescence, the MEDsan IgG rapid diagnostic test performed accurately.

Funder

Department of Woman, Child and Adolescent Medicine

Geneva University Hospitals and Faculty of Medicine

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciaa1702/34910037/ciaa1702.pdf

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