What Is the Primary Driver of Preoperative Vancomycin Use? It’s Not Methicillin-resistant Staphylococcus aureus—or Allergy

Author:

Strymish Judith M12,O’ Brien William2,Itani Kamal234,Gupta Kalpana145,Branch-Elliman Westyn125

Affiliation:

1. Department of Medicine, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA

2. Harvard Medical School, Boston, Massachusetts, USA

3. Department of Surgery, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA

4. Boston University School of Medicine, Boston, Massachusetts, USA

5. Veterans Affairs Center for Healthcare Organization and Implementation Research, Boston, Massachusetts, USA

Abstract

Abstract Factors driving vancomycin surgical prophylaxis are poorly understood. In a national Veterans Affairs cohort with manually validated data, surgical specialty (cardiac, orthopedics) and perception of high facility methicillin-resistant Staphylococcus aureus (MRSA) prevalence—not MRSA colonization—were the primary drivers of prescribing. A β-lactam allergy was the second most common reason. These data may inform perioperative stewardship.

Funder

Health Services Research and Development

National Heart, Lung, and Blood Institute

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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