Evaluation of the Tuberculosis Infection Care Cascade Among Pregnant Individuals in a Low-Tuberculosis-Burden Setting

Author:

Campbell Jeffrey I1ORCID,Lavache Dorine1,Garing Ariane1,Sabharwal Vishakha1,Haberer Jessica E2,Dubois Melanie3,Jenkins Helen E4,Brooks Meredith B5,Joseph Naima T6,Kissler Katherine7,Horsburgh C Robert5,Jacobson Karen R8

Affiliation:

1. Section of Pediatric Infectious Diseases, Boston Medical Center , Boston, Massachusetts , USA

2. Center for Global Health, Massachusetts General Hospital , Boston, Massachusetts , USA

3. Division of Pediatric Infectious Diseases, Weill Cornell Medical Center , New York, New York , USA

4. Department of Biostatistics, Boston University School of Public Health , Boston, Massachusetts , USA

5. Department of Global Health, Boston University School of Public Health , Boston, Massachusetts , USA

6. Department of Obstetrics and Gynecology, Boston Medical Center , Boston, Massachusetts , USA

7. College of Nursing, University of Colorado , Aurora, Colorado , USA

8. Division of Infectious Diseases, Boston Medical Center , Boston, Massachusetts , USA

Abstract

Abstract In the United States, tuberculosis (TB) screening is recommended for pregnant individuals with TB risk factors. We conducted a retrospective study of perinatal TB infection testing and treatment in a tertiary health system. Of 165 pregnant individuals with positive TB infection tests, only 9% completed treatment within 4.6 years of follow-up.

Funder

Joel and Barbara Alpert Endowment

for Children of the City

Boston-Providence Center for AIDS Research

National Institute of Allergy and Infectious Diseases

National Institutes of Health

Publisher

Oxford University Press (OUP)

Reference14 articles.

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3. Latent tuberculosis in pregnancy: a systematic review;Malhame;PLoS One,2016

4. Interferon gamma release assay tests are associated with persistence and completion of latent tuberculosis infection treatment in the United States: evidence from commercial insurance data;Stockbridge;PLoS One,2020

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