Simulation Modeling of Cancer Clinical Trials: Application to Omitting Radiotherapy in Low-risk Breast Cancer

Author:

Jayasekera Jinani1,Li Yisheng2,Schechter Clyde B3,Jagsi Reshma4,Song Juhee2,White Julia5,Luta George6,Chapman Judith-Anne W7,Feuer Eric J8,Zellars Richard C9,Stout Natasha10,Julian Thomas B11,Whelan Timothy12,Huang Xuelin2,Shelley Hwang E13,Hopkins Judith O14,Sparano Joseph A3,Anderson Stewart J15,Fyles Anthony W16,Gray Robert17,Sauerbrei Willi18,Mandelblatt Jeanne1,Berry Donald A2,Berry Donald A,Chapman Judith-Anne W,Costantino Joseph P,Fyles Anthony,Gray Robert,Hopkins Judith O,Huang Xuelin,Hwang E Shelley,Jagsi Reshma,Jayasekera Jinani,Julian Thomas B,Li Yisheng,Luta George,Mandelblatt Jeanne,Sauerbrei Willi,Schechter Clyde B,Sparano Joseph A,Song Juhee,Anderson Stewart J,Stout Natasha,Whelan Timothy,White Julia,Zellars Richard C,Feuer Eric J,

Affiliation:

1. Department of Oncology, Georgetown University Medical Center and Cancer Prevention and Control Program, Georgetown-Lombardi Comprehensive Cancer Center, Washington, DC

2. Department of Biostatistics, University of Texas M.D. Anderson Cancer Center, Houston, TX

3. Departments of Family and Social Medicine and Epidemiology and Population Health and Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY

4. Department of Radiation Oncology, University of Michigan, Ann Arbor, MI

5. Department of Radiation Oncology, The James, The Ohio State University Comprehensive Cancer Center, Columbus, OH

6. Department of Biostatistics, Bioinformatics and Biomathematics, Georgetown University Medical Center, Washington, DC

7. Canadian Cancer Trials Group, Queen’s University, Kingston, ON, Canada

8. Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD

9. Department of Radiation Oncology, Indiana University, Indianapolis, IN

10. Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA

11. NRG Oncology, and the Division of Breast Surgical Oncology, Allegheny General Hospital, Allegheny Health Network, Pittsburgh, PA

12. McMaster University and Hamilton Heath Sciences, Hamilton, ON, Canada

13. Department of Surgery, Duke Cancer Institute, Duke University Medical School, Chapel Hill, NC

14. Novant Health Oncology Specialists, Winston-Salem, NC

15. NRG Oncology, and the Department of Biostatistics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA

16. Cancer Clinical Research Unit, University of Toronto Princess Margaret Cancer Centre, Toronto, ON, Canada

17. Department of Biostatistics at Harvard University and Department of Biostatistics and Computational Biology at the Dana-Farber Cancer Institute, Boston, MA

18. Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany

Funder

National Institutes of Health

National Cancer Institute

American Society of Preventive Oncology

Breast Cancer Research Foundation

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Reference41 articles.

1. Randomized, controlled trials, observational studies, and the hierarchy of research designs;Concato;N Engl J Med,2000

2. Evidence for health decision making - beyond randomized, controlled trials;Frieden;N Engl J Med,2017

3. Clinical trial simulation in drug development;Girard;Therapie.,2004

4. Emerging innovations in clinical trial design;Berry;Clin Pharmacol Ther.,2016

5. Predicting clinical trial results based on announcements of interim analyses;Broglio;Trials.,2014

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3