Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump

Author:

Lorusso Roberto123ORCID,Heuts Samuel1ORCID,Jiritano Federica4ORCID,Scrofani Roberto5,Antona Carlo5ORCID,Actis Dato Guglielmo6ORCID,Centofanti Paolo6,Ferrarese Sandro7,Matteucci Matteo7,Miceli Antonio8ORCID,Glauber Mattia8,Vizzardi Enrico3,Sponga Sandro9,Vendramin Igor9ORCID,Garatti Andrea10ORCID,de Vincentis Carlo10,De Bonis Michele11ORCID,Ajello Silvia12,Troise Giovanni13,Dalla Tomba Margherita13,Serraino Filiberto4

Affiliation:

1. Department of Cardiothoracic Surgery, Maastricht University Medical Center+ , Maastricht, Netherlands

2. Cardiovascular Research Institute Maastricht (CARIM), Maastricht University , Maastricht, Netherlands

3. Department of Cardiac Surgery, A.O. Spedali Civili , Brescia, Italy

4. Department of Cardiac Surgery, Ospedale Universitario , Catanzaro, Italy

5. Department of Cardiac Surgery, Ospedale Sacco , Milan, Italy

6. Department of Cardiac Surgery, Ospedale Mauriziano , Torino, Italy

7. Department of Cardiac Surgery, Ospedale di Circolo , Varese, Italy

8. Department of Cardiac Surgery, Istituto Clinico S. Ambrogio , Milan, Italy

9. Department of Cardiac Surgery, Ospediale S. Maria della Misericordia , Udine, Italy

10. Department of Cardiac Surgery, Ospedale di S. Donato , Milan, Italy

11. Department of Cardiac Surgery, Ospedale S. Raffaele , Milan, Italy

12. Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute , Milan, Italy

13. Department of Cardiac Surgery, Ospedale Poliambulanza , Brescia, Italy

Abstract

Abstract OBJECTIVES Although the intra-aortic balloon pump (IABP) has been the most widely adopted temporary mechanical support device in cardiac surgical patients, its use has declined. The current study aimed to evaluate the occurrence and predictors of early mortality and complication rates in contemporary cardiac surgery patients supported by an IABP. METHODS A multicentre, retrospective analysis was performed of all consecutive cardiac surgical patients receiving perioperative balloon pump support in 8 centres between January 2010 to December 2019. The primary outcome was early mortality, and secondary outcomes were balloon-associated complications. A multivariable binary logistic regression model was applied to evaluate predictors of the primary outcome. RESULTS The study cohort consisted of 2615 consecutive patients. The median age was 68 years [25th percentile 61, 75th percentile 75 years], with the majority being male (76.9%), and a mean calculated 30-day mortality risk of 10.0%. Early mortality was 12.7% (n = 333), due to cardiac causes (n = 266), neurological causes (=22), balloon-related causes (n = 5) and other causes (n = 40). A composite end point of all vascular complications occurred in 7.2% of patients, and leg ischaemia was observed in 1.3% of patients. The most important predictors of early mortality were peripheral vascular disease [odds ratio (OR) 1.63], postoperative dialysis requirement (OR 10.40) and vascular complications (OR 2.57). CONCLUSIONS The use of the perioperative IABP proved to be safe and demonstrated relatively low complication rates, particularly for leg ischaemia. As such, we believe that specialists should not be held back to use this widely available treatment in high-risk cardiac surgical patients when indicated.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Pulmonary and Respiratory Medicine,Surgery

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3