Results of the Eighth Scientific Workshop of ECCO: Prevention and Treatment of Postoperative Recurrence in Patients With Crohn’s Disease Undergoing an Ileocolonic Resection With Ileocolonic Anastomosis

Author:

Ferrante Marc12ORCID,Pouillon Lieven3,Mañosa Míriam45,Savarino Edoardo67ORCID,Allez Matthieu8,Kapizioni Christina9,Arebi Naila10,Carvello Michele11,Myrelid Pär12ORCID,De Vries Annemarie C13,Dragoni Gabriele,Allocca Mariangela,Noor Nurulamin M,Bislenghi Gabriele,Hammoudi Nassim,Verstockt Bram,Brown Steven,Oliveira Cunha Melissa,Bemelman Willem,Pellino Gianluca,Kotze Paulo Gustavo,Rivière Pauline14ORCID,Panis Yves15ORCID,Domènech Eugeni45ORCID,

Affiliation:

1. Department of Gastroenterology and Hepatology, University Hospitals Leuven , Leuven , Belgium

2. Translational Research in Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (CHROMETA) , KU Leuven, Leuven , Belgium

3. Imelda GI Clinical Research Center, Imelda General Hospital , Bonheiden , Belgium

4. Department of Gastroenterology and Hepatology, Hospital Universitari Germans Trias i Pujol , Badalona , Spain

5. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) , Madrid , Spain

6. Department of Surgery, Oncology and Gastroenterology, University of Padua , Padua , Italy

7. Gastroenterology Unit, Azienda Ospedale Università di Padova , Padua , Italy

8. Gastroenterology Department, Hôpital Saint-Louis – APHP, Université Paris Cité , INSERM U1160, Paris , France

9. Department of Gastroenterology, Guy’s and St Thomas’ NHS Foundation Trust , London , UK

10. Department of Inflammatory Bowel Disease, St Mark’s Hospital , Harrow, London , UK

11. Department of Biomedical Sciences, Humanitas University , Milan , Italy

12. Department of Surgery, Linköping University Hospital and Department of Biomedical and Clinical Sciences, Linköping University , Linköping , Sweden

13. Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam , Rotterdam , the Netherlands

14. Department of Gastroenterology and Hepatology, Centre Médico-chirurgical Magellan, Hôpital Haut-Lévêque, CHU de Bordeaux, Université de Bordeaux , INSERM CIC 1401, Bordeaux , France

15. Paris IBD Center, Groupe Hospitalier Privé Ambroise-Paré Hartmann , Neuily/Seine , France

Abstract

Abstract Despite the introduction of biological therapies, an ileocolonic resection is often required in patients with Crohn’s disease [CD]. Unfortunately, surgery is not curative, as many patients will develop postoperative recurrence [POR], eventually leading to further bowel damage and a decreased quality of life. The 8th Scientific Workshop of ECCO reviewed the available scientific data on both prevention and treatment of POR in patients with CD undergoing an ileocolonic resection, dealing with conventional and biological therapies, as well as non-medical interventions, including endoscopic and surgical approaches in case of POR. Based on the available data, an algorithm for the postoperative management in daily clinical practice was developed.

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,General Medicine

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