Intestinal Activation of pH-Sensing Receptor OGR1 [GPR68] Contributes to Fibrogenesis-Reference-Cited by-同舟云学术

Intestinal Activation of pH-Sensing Receptor OGR1 [GPR68] Contributes to Fibrogenesis

Published:2018-08-25 Issue: Volume: Page:
ISSN:1873-9946
Container-title:Journal of Crohn's and Colitis
language:en
Short-container-title:

Author:

Hutter Senta¹,van Haaften Wouter T²³,Hünerwadel Anouk¹,Baebler Katharina¹,Herfarth Neel¹,Raselli Tina¹,Mamie Céline¹,Misselwitz Benjamin¹,Rogler Gerhard¹⁴,Weder Bruce¹,Dijkstra Gerard²,Meier Chantal Florence¹,de Vallière Cheryl¹,Weber Achim⁵,Imenez Silva Pedro H⁴⁶,Wagner Carsten A⁴^ORCID,Frey-Wagner Isabelle¹,Ruiz Pedro A¹,Hausmann Martin¹

Affiliation:

1. Department of Gastroenterology and Hepatology, University Hospital Zürich, Zürich, Switzerland

2. Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

3. Department of Pharmaceutical Technology and Biopharmacy, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands

4. Institute of Physiology, University of Zürich, Zürich, Switzerland

5. Department of Pathology and Molecular Pathology, University Hospital Zürich, Zürich, Switzerland

6. Kidney Control of Homeostasis, Swiss National Centre of Competence in Research, Zürich, Switzerland

Funder

FreeNovation

Swiss National Science Foundation

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,General Medicine

Link

http://academic.oup.com/ecco-jcc/advance-article-pdf/doi/10.1093/ecco-jcc/jjy118/25850648/jjy118.pdf

Reference61 articles.

1. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn’s disease susceptibility loci;Franke;Nat Genet,2010

2. Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease;Jostins;Nature,2012

3. The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment;de Vallière;Am J Physiol Gastrointest Liver Physiol,2015

4. G Protein-coupled pH-sensing receptor OGR1 is a regulator of intestinal inflammation;de Vallière;Inflamm Bowel Dis,2015

5. The proton-activated receptor GPR4 modulates intestinal inflammation;Wang;J Crohns Colitis,2018

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