Stability-Indicating Liquid Chromatographic Method for Determination of Saxagliptin and Structure Elucidation of the Major Degradation Products Using LC-MS-Reference-Cited by-同舟云学术

Stability-Indicating Liquid Chromatographic Method for Determination of Saxagliptin and Structure Elucidation of the Major Degradation Products Using LC-MS

Published:2014-07-24 Issue:4 Volume:53 Page:554-564
ISSN:0021-9665
Container-title:Journal of Chromatographic Science
language:en
Short-container-title:Journal of Chromatographic Science

Author:

Abdel-Ghany M. F.,Abdel-Aziz O.,Ayad M. F.,Tadros M. M.

Publisher

Oxford University Press (OUP)

Subject

General Medicine,Analytical Chemistry

Link

http://academic.oup.com/chromsci/article-pdf/53/4/554/994621/bmu084.pdf

Reference10 articles.

1. Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

2. Sensitive liquid chromatography tandem mass spectrometry method for the quantification of sitagliptin, a DPP-4 inhibitor, in human plasma using liquid–liquid extraction

3. Pharmacokinetics of the Dipeptidyl Peptidase 4 Inhibitor Saxagliptin in Rats, Dogs, and Monkeys and Clinical Projections

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