A retrospective comparison of early- and late-onset chronic actinic dermatitis: characteristics and management

Abstract

Our study highlights the high prevalence of early-onset chronic actinic dermatitis (CAD; age < 40 years at diagnosis), particularly in patients with atopic diseases and those with darker skin phototypes. Disease characteristics, photodiagnostic investigations and outcomes did not significantly differ between those with early-onset vs. late-onset disease, although younger patients more frequently required systemic therapy. We also show that marked UVA sensitivity and positive baseline series patch testing are negative prognostic factors for outcomes in CAD.