Addressing global disparities in blood pressure control: perspectives of the International Society of Hypertension

Author:

Schutte Aletta E123ORCID,Jafar Tazeen H45ORCID,Poulter Neil R6ORCID,Damasceno Albertino7ORCID,Khan Nadia A89,Nilsson Peter M10ORCID,Alsaid Jafar1112ORCID,Neupane Dinesh13ORCID,Kario Kazuomi14ORCID,Beheiry Hind15ORCID,Brouwers Sofie1617ORCID,Burger Dylan18ORCID,Charchar Fadi J1920ORCID,Cho Myeong-Chan21ORCID,Guzik Tomasz J22ORCID,Haji Al-Saedi Ghazi F23ORCID,Ishaq Muhammad24ORCID,Itoh Hiroshi25ORCID,Jones Erika S W26ORCID,Khan Taskeen27ORCID,Kokubo Yoshihiro28ORCID,Kotruchin Praew29ORCID,Muxfeldt Elizabeth30ORCID,Odili Augustine31ORCID,Patil Mansi32ORCID,Ralapanawa Udaya33ORCID,Romero Cesar A34ORCID,Schlaich Markus P353637ORCID,Shehab Abdulla38ORCID,Mooi Ching Siew39ORCID,Steckelings U Muscha40ORCID,Stergiou George41ORCID,Touyz Rhian M42ORCID,Unger Thomas43ORCID,Wainford Richard D44ORCID,Wang Ji-Guang45ORCID,Williams Bryan46ORCID,Wynne Brandi M47ORCID,Tomaszewski Maciej484950ORCID

Affiliation:

1. School of Population Health, University of New South Wales, Kensington Campus , High Street, Sydney 2052 NSW, Australia; The George Institute for Global Health, King Street, Newton, Sydney NSW 2052 , Australia

2. Hypertension in Africa Research Team, SAMRC Unit for Hypertension and Cardiovascular Disease; North-West University , Hoffman Street, Potchefstroom 2520 , South Africa

3. SAMRC Development Pathways for Health Research Unit, School of Clinical Medicine, University of the Witwatersrand , 1 Jan Smuts Ave, Braamfontein, Johannesburg, 2000 , South Africa

4. Program in Health Services and Systems Research, Duke-NUS Medical School, Department of Renal Medicine , 8 College Rd., Singapore 169857 , Singapore

5. Duke Global Health Institute, Duke University , 310 Trent Dr, Durham, NC 27710 , USA

6. Imperial Clinical Trials Unit, School of Public Health, Imperial College London , London W12 7RH , UK

7. Faculty of Medicine, Eduardo Mondlane University , 3453 Avenida Julius Nyerere, Maputo , Mozambique

8. Department of Medicine, University of British Columbia , Vancouver, British Columbia , Canada

9. Center for Health Evaluation and Outcomes Sciences , Vancouver, British Columbia , Canada

10. Department of Clinical Sciences, Skane University Hospital, Lund University , Malmö , Sweden

11. Ochsner Health System , New Orleans, Louisiana , USA

12. Queensland University , Brisbane, Queensland , Australia

13. Department of International Health, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University , Baltimore, MD , USA

14. Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine , Tochigi , Japan

15. International University of Africa , Khartoum , Sudan

16. Department of Cardiology, Cardiovascular Center Aalst, OLV Clinic Aalst , Aalst , Belgium

17. Department of Experimental Pharmacology, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel , Brussels , Belgium

18. Kidney Research Centre, Ottawa Hospital Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa , Ottawa, Ontario , Canada

19. Health Innovation and Transformation Centre, Federation University , Ballarat, Victoria , Australia

20. Department of Physiology and Anatomy, University of Melbourne , Melbourne, Victoria , Australia

21. Department of Internal Medicine, College of Medicine, Chungbuk National University , Cheongju , Korea

22. Institute of Cardiovascular and Medical Sciences, University of Glasgow , Glasgow , UK

23. Baghdad College of Medicine , Baghdad , Iraq

24. Pakistan Hypertension League , Karachi , Pakistan

25. Department of Endocrinology, Metabolism and Nephrology, School of Medicine, Keio University , 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8585 , Japan

26. Division of Nephrology and Hypertension, Groote Schuur Hospital and Kidney and Hypertension Research Unit, University of Cape Town , Cape Town , South Africa

27. Department of Public Health Medicine, University of Pretoria , Pretoria , South Africa

28. Department of Preventive Cardiology, National Cerebral and Cardiovascular Center , Osaka , Japan

29. Department of Emergency Medicine, Faculty of Medicine, Khon Kaen University , Khon Kaen , Thailand

30. University Hospital Clementino Fraga Filho, Hypertension Program, Universidade Federal do Rio de Janeiro , Brazil

31. Circulatory Health Research Laboratory, College of Health Sciences, University of Abuja , Abuja , Nigeria

32. Department of Nutrition and Dietetics, Asha Kiran JHC Hospital , Chinchwad , India

33. Faculty of Medicine, University of Peradeniya , Kandy, Central Province , Sri Lanka

34. Renal Division, Department of Internal Medicine, Emory University School of Medicine , Atlanta, GA , USA

35. Dobney Hypertension Centre, School of Medicine, Royal Perth Hospital Unit and RPH Research Foundation, The University of Western Australia , Perth , Australia

36. Department of Cardiology, Royal Perth Hospital , Perth, Western Australia , Australia

37. Department of Nephrology, Royal Perth Hospital , Perth, Western Australia, Perth, Western Australia , Australia

38. College of Medicine and Health Sciences, United Arab Emirates University , Al Ain , United Arab Emirates

39. Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia , Malaysia

40. Department of Cardiovascular & Renal Research, Institute of Molecular Medicine. University of Southern Denmark , Odense , Denmark

41. Hypertension Centre STRIDE-7, School of Medicine, Third Department of Medicine, Sotiria Hospital, National and Kapodistrian University of Athens , Athens , Greece

42. Research Institute of the McGill University Health Centre, McGill University , Montreal, QC , Canada

43. CARIM - Cardiovascular Research Institute, Maastricht University , Maastricht , The Netherlands

44. Department of Pharmacology & Experimental Therapeutics and the Whitaker, Cardiovascular Institute, Boston University School of Medicine , Boston, MA , USA

45. Department of Hypertension, Centre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , China

46. Institute of Cardiovascular Science, University College London (UCL), National Institute for Health Research (NIHR), UCL Hospitals Biomedical Research Centre , London , UK

47. Department of Internal Medicine, Division of Nephrology & Hypertension, University of Utah , Salt Lake City, UT , USA

48. Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester , Manchester , UK

49. Manchester Heart Centre, Manchester University NHS Foundation Trust , Manchester , UK

50. Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust , Manchester , UK

Abstract

Abstract Abstract Raised blood pressure (BP) is the leading cause of preventable death in the world. Yet, its global prevalence is increasing, and it remains poorly detected, treated, and controlled in both high- and low-resource settings. From the perspective of members of the International Society of Hypertension based in all regions, we reflect on the past, present, and future of hypertension care, highlighting key challenges and opportunities, which are often region-specific. We report that most countries failed to show sufficient improvements in BP control rates over the past three decades, with greater improvements mainly seen in some high-income countries, also reflected in substantial reductions in the burden of cardiovascular disease and deaths. Globally, there are significant inequities and disparities based on resources, sociodemographic environment, and race with subsequent disproportionate hypertension-related outcomes. Additional unique challenges in specific regions include conflict, wars, migration, unemployment, rapid urbanization, extremely limited funding, pollution, COVID-19-related restrictions and inequalities, obesity, and excessive salt and alcohol intake. Immediate action is needed to address suboptimal hypertension care and related disparities on a global scale. We propose a Global Hypertension Care Taskforce including multiple stakeholders and societies to identify and implement actions in reducing inequities, addressing social, commercial, and environmental determinants, and strengthening health systems implement a well-designed customized quality-of-care improvement framework.

Funder

National Medical Research Council

National Institutes of Health

National Health and Medical Research Council

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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