Antinuclear antibodies in neurology and their clinical application

Author:

Sudheer Pachipala1,Agarwal Ayush1ORCID,Vishnu Venugopalan Y1ORCID

Affiliation:

1. From the Department of Neurology, All India Institute of Medical Sciences, New Delhi, 110029 India

Abstract

Abstract Antinuclear antibodies (ANA) are a diverse group of autoantibodies found in various systemic autoimmune disorders. They represent a key diagnostic marker in the diagnosis of connective tissue disorders (CTD). Although many techniques exist, ANA by indirect immunofluorescence remains the gold standard for diagnosing CTDs. Neurologists should be aware of the type of assay used for detection and the advantages and disadvantages of using each method. Through this article, we aimed to review the methodological aspects of the detection of ANA and its subtypes and their clinical relevance in various neurologic disorders.

Publisher

Oxford University Press (OUP)

Subject

General Medicine

Reference42 articles.

1. Antinuclear antibodies: clinical applications;Wanchu;J Postgrad Med,2000

2. Presentation of two bone marrow elements; the tart cell and the L.E. cell;Hargraves;Proc Staff Meet Mayo Clin,1948

3. Identification of the nuclear component of the interaction of lupus erythematosus globulin and nuclei;Friou;J Immunol (Baltimore Md.),1950

4. Clinical application of a test for lupus globulin-nucleohistone interaction using fluorescent antibody;Friou;Yale J Biol Med,1958

5. Improved method for measuring lupus globulin-nucleoprotein interaction;Friou;Proc Soc Exp Biol Med Soc Exp Biol Med N Y N,1958

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3