Surgical Treatment With Thoracic Pedicle Screw Fixation of Vertebral Osteomyelitis With Long-Term Follow-up

Author:

Heary Robert F1,Agarwal Nitin2,Agarwal Prateek3,Goldstein Ira M1

Affiliation:

1. Department of Neurological Surgery, Rutgers New Jersey Medical School, Newark, New Jersey

2. Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

3. Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

Abstract

Abstract BACKGROUND While recent data has demonstrated the utility of lumbar pedicle screws for the treatment of vertebral osteomyelitis, the data are limited for thoracic pedicle screws. OBJECTIVE To investigate the effectiveness of thoracic pedicle screws for the surgical treatment of vertebral osteomyelitis. METHODS A retrospective review of all operations performed by 2 spinal neurosurgeons from 1999 to 2012 yielded 30 cases of vertebral osteomyelitis that were treated with thoracic pedicle screws. Sixteen (53%) of which underwent combined anterior and posterior fusion and 14 patients (47%) underwent standalone posterior fusion. Postoperative records were analyzed for pertinent clinical, laboratory, and radiographic data. RESULTS Of the 30 patients, 21 were males (70%), 8 were females (27%), and 1 was transsexual (3%). The mean age was 47 yr (range 18-69). The most common organism cultured was Staphylococcus aureus in 12 cases (50%). The mean patient stay in the hospital was 12.4 d after surgery (range 5-38 d). The mean antibiotic duration after discharge was 8 wk (range 1-24 wk). Of the 25 patients with long-term follow-up (mean, 49 mo), 92% had improved back pain (6/25 marked improvement, 17/25 complete resolution), 83% had improved muscle weakness (8/18 marked improvement, 7/18 complete resolution), and 100% had improved urinary incontinence (3/8 marked improvement, 5/8 complete resolution). Two patients (7%) required additional surgical revision due to instrumentation failure or wound infection. CONCLUSION This study demonstrates the efficacy of utilizing thoracic pedicle screws as a primary intervention to treat vertebral osteomyelitis.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Neurology (clinical),Surgery

Reference55 articles.

1. Vertebral osteomyelitis: long-term outcome for 253 patients from 7 Cleveland-area hospitals;McHenry;Clin Infect Dis,2002

2. Vertebral osteomyelitis in Goteborg, Sweden: a retrospective study of patients during 1990–95;Beronius;Scand J Infect Dis,2001

3. Epidemiology of vertebral osteomyelitis (VO) in France: analysis of hospital-discharge data 2002–2003;Grammatico;Epidemiol Infect,2008

4. Increasing incidence of pyogenic spondylodiscitis: a 14-year population-based study;Kehrer;J Infection,2014

5. Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics;Mylona;Semin Arthritis Rheu,2009

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