Waning Immunity Against Respiratory Syncytial Virus During the Coronavirus Disease 2019 Pandemic-Reference-Cited by-同舟云学术

Waning Immunity Against Respiratory Syncytial Virus During the Coronavirus Disease 2019 Pandemic

Published:2022-05-07 Issue:12 Volume:226 Page:2064-2068
ISSN:0022-1899
Container-title:The Journal of Infectious Diseases
language:en
Short-container-title:

Author:

Reicherz Frederic¹²,Xu Rui Yang¹²,Abu-Raya Bahaa¹²,Majdoubi Abdelilah¹²,Michalski Christina¹²,Golding Liam¹³,Stojic Aleksandra⁴,Vineta Marina¹³,Granoski Madison⁴,Cieslak Zenon⁵,Chacko Anil⁶,Desai Neil²,Sekirov Inna⁷⁸,Marchant David J⁴,Lavoie Pascal M¹²

Affiliation:

1. British Columbia Children’s Hospital Research Institute , Vancouver , Canada

2. Department of Pediatrics, Faculty of Medicine, University of British Columbia , Vancouver , Canada

3. Reproductive and Developmental Sciences Program, Department of Obstetrics and Gynecology, University of British Columbia , Vancouver , Canada

4. Li Ka Shing Institute of Virology, Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, University of Alberta , Edmonton , Canada

5. Department of Pediatrics, Royal Columbian Hospital , New Westminster , Canada

6. Department of Pediatrics, Surrey Memorial Hospital , Surrey , Canada

7. British Columbia Centre for Disease Control Public Health Laboratory , Vancouver , Canada

8. Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia , Vancouver , Canada

Abstract

Abstract Health jurisdictions have seen a near-disappearance of respiratory syncytial virus (RSV) during the first year of the coronavirus disease 2019 (COVID-19) pandemic. Over this corresponding period, we report a reduction in RSV antibody levels and live virus neutralization in sera from women of childbearing age and infants between May to June 2020 and February to June 2021, in British Columbia (BC), Canada. This supports that antibody immunity against RSV is relatively short-lived and that maintaining optimal antibody levels in infants requires repeated maternal viral exposure. Waning immunity may explain the interseasonal resurgence of RSV cases observed in BC and other countries.

Funder

Government of Canada

German Research Foundation

Deutsche Forschungsgemeinschaft

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Link

https://academic.oup.com/jid/advance-article-pdf/doi/10.1093/infdis/jiac192/43890186/jiac192.pdf

Reference13 articles.

1. The impact of COVID-19 public health measures on detections of influenza and respiratory syncytial virus in children during the 2020 Australian winter;Yeoh;Clin Infect Dis,2020