Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria: An Open-Label, Phase 1, Dose-Adjustment Trial

Author:

Chen Ingrid12,Diawara Halimatou3,Mahamar Almahamoudou3,Sanogo Koualy3,Keita Sekouba3,Kone Daouda3,Diarra Kalifa3,Djimde Moussa3,Keita Mohamed4,Brown Joelle2,Roh Michelle E12,Hwang Jimee15,Pett Helmi67,Murphy Maxwell8,Niemi Mikko7,Greenhouse Bryan8,Bousema Teun69,Gosling Roly12,Dicko Alassane3

Affiliation:

1. Malaria Elimination Initiative, Global Health Group, San Francisco

2. Department of Epidemiology and Biostatistics, San Francisco

3. Malaria Research and Training Centre, Faculty of Pharmacy and Faculty of Medicine and Dentistry, University of Science, Techniques and Technologies of Bamako

4. National University Hospital of Point G, Bamako, Mali

5. President’s Malaria Initiative, Malaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia

6. Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands

7. Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, Finland

8. School of Medicine, University of California, San Francisco

9. Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, United Kingdom

Funder

Bill and Melinda Gates Foundation

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

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