Hepatitis B Surface Antigen Loss: What Does Integration Have to Do With a Functional Hepatitis B Virus Cure?
Author:
Affiliation:
1. Department of Medicine, Johns Hopkins University School of Medicine , Baltimore, Maryland , USA
Funder
National Institute of Allergy and Infectious Diseases
Publisher
Oxford University Press (OUP)
Link
https://academic.oup.com/jid/advance-article-pdf/doi/10.1093/infdis/jiae327/58540918/jiae327.pdf
Reference15 articles.
1. Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019;GBD 2019 Hepatitis B Collaborators;Lancet Gastroenterol Hepatol,2022
2. Integrated HBV DNA and cccDNA maintain transcriptional activity in intrahepatic HBsAg-positive patients with functional cure following PEG-IFN-based therapy;Gao;Aliment Pharmacol Ther,2023
3. Hepatitis B virus DNA and RNA persist in liver after serologic recovery in persons with hepatitis C virus;Grudda;J Infect Dis,2024
4. HBV DNA integration: molecular mechanisms and clinical implications;Tu;Viruses,2017
5. Single hepatocytes show persistence and transcriptional inactivity of hepatitis B;Balagopal;JCI Insight,2020
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