Affiliation:
1. Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA
2. Department of Medicine, Brown University, Providence, Rhode Island, USA
Abstract
Abstract
Background
Coronavirus disease 2019 (COVID-19) has spread rapidly in the United States since January 2020.
Methods
We estimated mean epidemic doubling time, an important measure of epidemic growth, nationally, by state, and in association with stay-at-home orders.
Results
The epidemic doubling time in the United States was 2.68 days (95% confidence interval [CI], 2.30–3.24 days) before widespread mitigation efforts, increasing by 460% to 15 days (12.89–17.94 days) during the mitigation phase. Among states without stay-at-home orders, the median increase in doubling time was 60% (95% CI, 9.2–223.3), compared with 269% (95% CI, 277.0–394.0) for states with stay-at-home orders.
Conclusions
Statewide mitigation strategies were strongly associated with increased epidemic doubling time.
Publisher
Oxford University Press (OUP)
Subject
Infectious Diseases,Immunology and Allergy
Cited by
31 articles.
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