A Rare Etiology for Ascending Paralysis in an Infant

Author:

Abe Keisuke1ORCID,Casamina Chanel2,Ching Natascha2,Abe Keith K2,Melish Marian2,Thompson Karen S3,Ahmed Asim A4,Purohit Prashant J2

Affiliation:

1. Department of Emergency Medicine, University of New Mexico School of Medicine , Albuquerque, New Mexico , USA

2. Department of Pediatrics, John A. Burns School of Medicine, University of Hawaiʹi at Manoa , Honolulu, Hawaii , USA

3. Department of Pathology, John A. Burns School of Medicine, University of Hawaiʹi at Manoa , Honolulu, Hawaii , USA

4. Vice President of Medical Affairs , Karius, Redwood City, California , USA

Abstract

Abstract An 11-month-old male infant with ascending paralysis had an unremarkable initial cerebrospinal fluid (CSF) analysis and imaging. Progressive neurological symptoms resulted in repeated CSF sampling, microscopy, and plasma microbial cell-free DNA next-generation sequencing analysis, that in combination with epidemiology, confirmed the diagnosis.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,General Medicine,Pediatrics, Perinatology and Child Health

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