Are Many Patients Diagnosed With Healthcare-associated Clostridioides difficile Infections Colonized With the Infecting Strain on Admission?-Reference-Cited by-同舟云学术

Are Many Patients Diagnosed With Healthcare-associated Clostridioides difficile Infections Colonized With the Infecting Strain on Admission?

Published:2019-03-11 Issue:10 Volume:69 Page:1801-1804
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Gonzalez-Orta Melany¹²,Saldana Carlos¹²,Ng-Wong Yilen¹,Cadnum Jennifer¹,Jencson Annette¹,Jinadatha Chetan³⁴,Donskey Curtis J⁵⁶

Affiliation:

1. Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland Clinic Foundation, Ohio

2. Department of Medicine, Cleveland Clinic Foundation, Ohio

3. Department of Medicine, Central Texas Veterans Health Care System, Temple, Texas A&M University, Bryan

4. College of Medicine, Texas A&M University, Bryan

5. Geriatric Research, Education, and Clinical Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio

6. Case Western Reserve University School of Medicine, Cleveland, Ohio

Abstract

Abstract In a cohort of 480 patients admitted to an acute care hospital, 68 (14%) had positive perirectal cultures for toxigenic Clostridioides difficile on admission. Of the 11 patients (2%) diagnosed with healthcare-associated C. difficile infections, 3 (27%) had genetically related admission and infection isolates, based on whole-genome sequencing.

Funder

U.S. Department of Veterans Affairs

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciz189/28533300/ciz189.pdf

Reference12 articles.

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3. Transmission of Clostridium difficile from asymptomatically colonized or infected long-term care facility residents;Donskey;Infect Control Hosp Epidemiol,2018