Development of a target product profile for a One Health antimicrobial resistance surveillance service

Abstract

Abstract We developed a target product profile (TPP) for an interoperable, nationally hosted surveillance service that can automatically aggregate One Health antimicrobial resistance (AMR) data from numerous sources. The service described would provide a customized view of national level data in low- and middle-income countries. A draft TPP was reviewed through online survey by experts with broad knowledge across AMR policy, microbiology, surveillance and data management. The TPP included 51 characteristics with minimal and optimal requirements relating to overall information technology (IT) vision of effective AMR surveillance, data characteristics, data storage and use, interoperability, data security, system management and governance and non-functional requirements. The agreement for all characteristics in Round 1 was high (≥85%). Ten characteristics for which comments highlighted a need for clarification were amended and circulated for further review among 28 non-commercial and 15 commercial reviewers who responded to Round 1. The agreement with these characteristics during Round 2 was ≥88%. The final TPP will serve as an informative tool for a variety of stakeholders including diagnostic and software developers, governments and policymakers. The TPP aims to promote development of effective AMR surveillance information technology approaches to support policy decisions and implementation across human health, animal health and other sectors.