Serum Cortisol and Cortisone as Potential Biomarkers of Partial 11β-Hydroxysteroid Dehydrogenase Type 2 Deficiency

Author:

Carvajal Cristian A12ORCID,Tapia-Castillo Alejandra123,Valdivia Carolina P1,Allende Fidel4,Solari Sandra4,Lagos Carlos F125,Campino Carmen12ORCID,Martínez-Aguayo Alejandro6,Vecchiola Andrea12,Pinochet Constanza6,Godoy Claudia6,Iturrieta Virginia1,Baudrand Rene1,Fardella Carlos E12

Affiliation:

1. Department of Endocrinology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile

2. Millennium Institute on Immunology and Immunotherapy (IMII), Santiago, Chile

3. Faculty of Medicine, Universidad del Desarrollo, Santiago, Chile

4. Department of Clinical Laboratories, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile

5. Facultad de Ciencia, Universidad San Sebastián, Santiago, Chile

6. Endocrinology Pediatrics Division, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile

Publisher

Oxford University Press (OUP)

Subject

Internal Medicine

Reference40 articles.

1. Inherited forms of mineralocorticoid hypertension;Hassan-Smith;Curr Opin Endocrinol Diabetes Obes,2011

2. Two homozygous mutations in the 11 beta-hydroxysteroid dehydrogenase type 2 gene in a case of apparent mineralocorticoid excess;Carvajal;J Clin Endocrinol Metab,2003

3. Overexpression of 11β-hydroxysteroid dehydrogenase type 1 in visceral adipose tissue and portal hypercortisolism in non-alcoholic fatty liver disease;Candia;Liver Int,2012

4. A new presentation of the chimeric CYP11B1/CYP11B2 gene with low prevalence of primary aldosteronism and atypical gene segregation pattern;Carvajal;Hypertension,2012

5. Increased urinary glucocorticoid metabolites are associated with metabolic syndrome, hypoadiponectinemia, insulin resistance and β cell dysfunction;Baudrand;Steroids,2011

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