Laryngeal Chemoreflex in Health and Disease: A Review-Reference-Cited by-同舟云学术

Laryngeal Chemoreflex in Health and Disease: A Review

Published:2020-10-14 Issue:9 Volume:45 Page:823-831
ISSN:0379-864X
Container-title:Chemical Senses
language:en
Short-container-title:

Author:

Pathak Shivani¹,Slovarp Laurie²,Clary Matthew S¹,Jetté Marie E¹

Affiliation:

1. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado, Aurora, CO, USA

2. School of Speech, Language, Hearing, & Occupational Sciences, University of Montana, Missoula, MT, USA

Abstract

Abstract The larynx plays a key role in airway protection via the laryngeal chemoreflex (LCR). This involuntary reflex can be evoked when hazardous substances activate mucosal receptors, which send signals to be processed within the brainstem. Although the LCR is meant to be protective, the reflex can become hyperstimulated, even to benign stimuli, which can result in pathological disorders, such as chronic cough and inducible laryngeal obstruction. In this review, we will outline the mechanism of the LCR and its associated pathological disorders.

Funder

National Institute on Deafness and Other Communication Disorders

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Behavioral Neuroscience,Physiology (medical),Sensory Systems,Physiology

Link

http://academic.oup.com/chemse/advance-article-pdf/doi/10.1093/chemse/bjaa069/34565839/bjaa069.pdf

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