Dermorphin: A Missed Palliative Care Opportunity for Intrathecal Therapy in Oncological Patients?

Author:

Liebregts Remko1,Keppel Hesselink Jan M23,Kopsky David J3

Affiliation:

1. Department of Anaesthesiology and Pain Medicine - Location VUmc, Amsterdam University Medical Center, Amsterdam, The Netherlands

2. Faculty of Health, University of Witten/Herdecke, Witten, Germany

3. Institute for Neuropathic Pain, Amsterdam, The Netherlands

Publisher

Oxford University Press (OUP)

Subject

Anesthesiology and Pain Medicine,Neurology (clinical),General Medicine

Reference11 articles.

1. Intrathecal administration of high-dose morphine solutions decreases the pH of cerebrospinal fluid;Wagemans;Pain,1995

2. Separation of opioid analgesia from respiratory depression: Evidence for different receptor mechanisms;Ling;J Pharmacol Exp Ther,1985

3. Intrathecal granuloma formation as result of opioid delivery: Systematic literature review of case reports and analysis against a control group;Duarte;Clin Neurol Neurosurg,2012

4. Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine;De Conno;Pain,1991

5. Biphalin, a dimeric enkephalin, alleviates LPS-induced activation in rat primary microglial cultures in opioid receptor-dependent and receptor-independent manners;Popiolek-Barczyk;Neural Plast,2017

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