1. Nottingham Centre for Public Health and Epidemiology , School of Medicine, , Nottingham NG5 1PB , United Kingdom
2. The University of Nottingham, Clinical Sciences Building, Nottingham City Hospital , School of Medicine, , Nottingham NG5 1PB , United Kingdom
3. SPECTRUM Consortium , United Kingdom
4. The Nottingham Centre for Evidence-Based Healthcare , School of Medicine, , Nottingham NG5 1PB , United Kingdom