“Spin” among abstracts of randomized controlled trials in sleep medicine: a research-on-research study

Author:

Guo Feiyang12,Zhao Tingting123,Zhai Qianglan1,Fang Xiaolin1,Yue Haoze4,Hua Fang3567ORCID,He Hong123ORCID

Affiliation:

1. Hubei-MOST KLOS and KLOBM, School and Hospital of Stomatology, Wuhan University , Wuhan , China

2. Department of Orthodontics, School and Hospital of Stomatology, Wuhan University , Wuhan , China

3. Center for Dentofacial Development and Sleep Medicine, School and Hospital of Stomatology, Wuhan University , Wuhan , China

4. Department of Epidemiology and Public Health, University College London , London , UK

5. Center for Evidence-Based Stomatology, School and Hospital of Stomatology, Wuhan University , Wuhan , China

6. Center for Orthodontics and Pediatric Dentistry, Optics Valley Branch, School and Hospital of Stomatology, Wuhan University , Wuhan , China

7. Division of Dentistry, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester , Manchester , UK

Abstract

Abstract Study Objectives “Spin,” using reporting strategies to distort study results, can mislead readers of medical research. This study aimed to evaluate the prevalence and characteristics of “spin” among randomized controlled trial (RCT) abstracts published in sleep medicine journals, and to identify factors associated with its presence and severity. Methods The search for RCTs published between 2010 and 2020 were conducted in seven reputable journals of sleep medicine. Abstracts of RCTs with statistically nonsignificant primary outcomes were included and analyzed for “spin,” according to predetermined “spin” strategies. Chi-square tests or logistic regression analyses were performed to detect the association between characteristics of included abstracts and the presence and severity of “spin.” Results A total of 114 RCT abstracts were included in this study, of which 89 (78.1%) were identified as having at least one type of “spin” strategy. Sixty-six abstracts (57.9%) had “spin” in the Results section, 82 (71.9%) abstracts presented with “spin” in the Conclusions section. The presence of “spin” varied significantly among RCTs based on the different categories of research area (p = 0.047) and the statistician involvement (p = 0.045). Furthermore, research area (p = 0.019) and funding status (p = 0.033) were significant factors associated with the severity of “spin.” Conclusions The prevalence of “spin” is high among RCT abstracts in sleep medicine. This raises the need for researchers, editors, and other stakeholders to be aware of the issue of “spin” and make joint efforts to eliminate it in future publications.

Funder

Chinese Stomatological Association Chinese Orthodontic Society Basic Research Fund

Chinese Stomatological Association Orthodontic Clinical Research Project for Central and West China

Wuhan University School of Medicine Teaching Research Project

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Neurology (clinical)

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