MetaNetX/MNXref: unified namespace for metabolites and biochemical reactions in the context of metabolic models

Author:

Moretti Sébastien1ORCID,Tran Van Du T1ORCID,Mehl Florence1ORCID,Ibberson Mark1,Pagni Marco1ORCID

Affiliation:

1. Vital-IT group, SIB Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland

Abstract

Abstract MetaNetX/MNXref is a reconciliation of metabolites and biochemical reactions providing cross-links between major public biochemistry and Genome-Scale Metabolic Network (GSMN) databases. The new release brings several improvements with respect to the quality of the reconciliation, with particular attention dedicated to preserving the intrinsic properties of GSMN models. The MetaNetX website (https://www.metanetx.org/) provides access to the full database and online services. A major improvement is for mapping of user-provided GSMNs to MXNref, which now provides diagnostic messages about model content. In addition to the website and flat files, the resource can now be accessed through a SPARQL endpoint (https://rdf.metanetx.org).

Funder

Swiss Federal Government

Swiss National Science Foundation

Publisher

Oxford University Press (OUP)

Subject

Genetics

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