Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2021

Author:

,Xue Yongbiao,Bao Yiming,Zhang Zhang,Zhao Wenming,Xiao Jingfa,He Shunmin,Zhang Guoqing,Li Yixue,Zhao Guoping,Chen Runsheng,Song Shuhui,Ma Lina,Zou Dong,Tian Dongmei,Li Cuiping,Zhu Junwei,Gong Zheng,Chen Meili,Wang Anke,Ma Yingke,Li Mengwei,Teng Xufei,Cui Ying,Duan Guangya,Zhang Mochen,Jin Tong,Shi Chengmin,Du Zhenglin,Zhang Yadong,Liu Chuandong,Li Rujiao,Zeng Jingyao,Hao Lili,Jiang Shuai,Chen Hua,Han Dali,Xiao Jingfa,Zhang Zhang,Zhao Wenming,Xue Yongbiao,Bao Yiming,Zhang Tao,Kang Wang,Yang Fei,Qu Jing,Zhang Weiqi,Bao Yiming,Liu Guang-Hui,Liu Lin,Zhang Yang,Niu Guangyi,Zhu Tongtong,Feng Changrui,Liu Xiaonan,Zhang Yuansheng,Li Zhao,Chen Ruru,Li Qianpeng,Teng Xufei,Ma Lina,Hua Zhongyi,Tian Dongmei,Jiang Chao,Chen Ziyuan,He Fangshu,Zhao Yuyang,Jin Yan,Zhang Zhang,Huang Luqi,Song Shuhui,Yuan Yuan,Zhou Chenfen,Xu Qingwei,He Sheng,Ye Wei,Cao Ruifang,Wang Pengyu,Ling Yunchao,Yan Xing,Wang Qingzhong,Zhang Guoqing,Li Zhao,Liu Lin,Jiang Shuai,Li Qianpeng,Feng Changrui,Du Qiang,Ma Lina,Zong Wenting,Kang Hongen,Zhang Mochen,Xiong Zhuang,Li Rujiao,Huan Wendi,Ling Yunchao,Zhang Sirui,Xia Qiguang,Cao Ruifang,Fan Xiaojuan,Wang Zefeng,Zhang Guoqing,Chen Xu,Chen Tingting,Zhang Sisi,Tang Bixia,Zhu Junwei,Dong Lili,Zhang Zhewen,Wang Zhonghuang,Kang Hailong,Wang Yanqing,Ma Yingke,Wu Song,Kang Hongen,Chen Meili,Li Cuiping,Tian Dongmei,Tang Bixia,Liu Xiaonan,Teng Xufei,Song Shuhui,Tian Dongmei,Liu Xiaonan,Li Cuiping,Teng Xufei,Song Shuhui,Zhang Yuansheng,Zou Dong,Zhu Tongtong,Chen Ming,Niu Guangyi,Liu Chang,Xiong Yujia,Hao Lili,Niu Guangyi,Zou Dong,Zhu Tongtong,Shao Xueying,Hao Lili,Li Yanyan,Zhou Honghong,Chen Xiaomin,Zheng Yu,Kang Quan,Hao Di,Zhang Lili,Luo Huaxia,Hao Yajing,Chen Runsheng,Zhang Peng,He Shunmin,Zou Dong,Zhang Mochen,Xiong Zhuang,Nie Zhi,Yu Shuhuan,Li Rujiao,Li Mengwei,Li Rujiao,Bao Yiming,Xiong Zhuang,Li Mengwei,Yang Fei,Ma Yingke,Sang Jian,Li Zhaohua,Li Rujiao,Tang Bixia,Zhang Xiangquan,Dong Lili,Zhou Qing,Cui Ying,Zhai Shuang,Zhang Yaping,Wang Guodong,Zhao Wenming,Wang Zhonghuang,Zhu Qianghui,Li Xin,Zhu Junwei,Tian Dongmei,Kang Hailong,Li Cuiping,Zhang Sisi,Song Shuhui,Li Menghua,Zhao Wenming,Yan Jun,Sang Jian,Zou Dong,Li Chen,Wang Zhennan,Zhang Yuansheng,Zhu Tongtong,Song Shuhui,Wang Xiangfeng,Hao Lili,Liu Yuanming,Wang Zhonghuang,Luo Hong,Zhu Junwei,Wu Xiaoyuan,Tian Dongmei,Li Cuiping,Zhao Wenming,Jing Hai-Chun,Chen Ming,Zou Dong,Hao Lili,Zhao Lianhe,Wang Jiajia,Li Yanyan,Song Tinrui,Zheng Yu,Chen Runsheng,Zhao Yi,He Shunmin,Zou Dong,Mehmood Furrukh,Ali Shahid,Ali Amjad,Saleem Shoaib,Hussain Irfan,Abbasi Amir A,Ma Lina,Zou Dong,Zou Dong,Jiang Shuai,Zhang Zhang,Jiang Shuai,Zhao Wenming,Xiao Jingfa,Bao Yiming,Zhang Zhang,Zuo Zhixiang,Ren Jian,Zhang Xinxin,Xiao Yun,Li Xia,Zhang Xinxin,Xiao Yun,Li Xia,Tu Yiran,Xue Yu,Wu Wanying,Ji Peifeng,Zhao Fangqing,Meng Xianwen,Chen Ming,Peng Di,Xue Yu,Luo Hao,Gao Feng,Zhang Xinxin,Xiao Yun,Li Xia,Ning Wanshan,Xue Yu,Lin Shaofeng,Xue Yu,Liu Teng,Guo An-Yuan,Yuan Hao,Zhang Yong E,Tan Xiaodan,Xue Yu,Zhang Weizhi,Xue Yu,Xie Yubin,Ren Jian,Wang Chenwei,Xue Yu,Liu Chun-Jie,Guo An-Yuan,Yang De-Chang,Tian Feng,Gao Ge,Tang Dachao,Xue Yu,Yao Lan,Xue Yu,Cui Qinghua,An Ni A,Li Chuan-Yun,Luo XiaoTong,Ren Jian,Zhang Xinxin,Xiao Yun,Li Xia

Abstract

Abstract The National Genomics Data Center (NGDC), part of the China National Center for Bioinformation (CNCB), provides a suite of database resources to support worldwide research activities in both academia and industry. With the explosive growth of multi-omics data, CNCB-NGDC is continually expanding, updating and enriching its core database resources through big data deposition, integration and translation. In the past year, considerable efforts have been devoted to 2019nCoVR, a newly established resource providing a global landscape of SARS-CoV-2 genomic sequences, variants, and haplotypes, as well as Aging Atlas, BrainBase, GTDB (Glycosyltransferases Database), LncExpDB, and TransCirc (Translation potential for circular RNAs). Meanwhile, a series of resources have been updated and improved, including BioProject, BioSample, GWH (Genome Warehouse), GVM (Genome Variation Map), GEN (Gene Expression Nebulas) as well as several biodiversity and plant resources. Particularly, BIG Search, a scalable, one-stop, cross-database search engine, has been significantly updated by providing easy access to a large number of internal and external biological resources from CNCB-NGDC, our partners, EBI and NCBI. All of these resources along with their services are publicly accessible at https://bigd.big.ac.cn.

Funder

Chinese Academy of Sciences

National Key Research and Development Program of China

National Natural Science Foundation of China

Genomics Data Center Construction of Chinese Academy of Sciences

Fundamental Research Funds for the Central Universities

UK Royal Society-Newton Advanced Fellowship

Key Research Program of Frontier Sciences of the Chinese Academy of Sciences

Key Technology Talent Program of the Chinese Academy of Sciences

K. C. Wong Education Foundation

National Key Research and Development Program

China Postdoctoral Science Foundation

Ministry of Science and Technology

National Science and Technology Basic Resources Investigation

Key Research Program of the Chinese Academy of Sciences

Zhangjiang special project of national innovation demonstration zone

Publisher

Oxford University Press (OUP)

Subject

Genetics

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